Plain-English translation of NCT05139277 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Glioblastoma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are testing a device called the CONVIVO system — a special imaging camera that uses a fluorescent dye to help surgeons better see tumor tissue versus healthy tissue during brain tumor surgery. The images from this camera will be compared to standard laboratory analysis of tissue samples to see how accurate the system is. This is the first study of its kind to test whether this camera can truly help surgeons tell the difference between normal and abnormal brain tissue during an operation.
Removing as much tumor as possible during surgery helps patients live longer and delay cancer recurrence, but surgeons often struggle to see exactly where the tumor ends and healthy brain begins. This medication aims to solve that problem by giving surgeons real-time visual guidance to help them remove more tumor while protecting healthy tissue.
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If you join this study, the special imaging camera and fluorescent dye will be used during your already-planned brain tumor surgery. After the surgeon uses the camera to image a specific area of tissue, a small sample will be collected and sent to the lab for traditional analysis so researchers can compare the camera results with the gold-standard tissue examination. The study does not change your surgery or require extra visits — it simply adds a diagnostic step during your operation to help evaluate how well the camera works.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
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