Plain-English translation of NCT05147909 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand whether eating too much phosphate (a mineral found in many foods) makes it harder for your muscles to work during exercise. This trial will ask you to take sodium phosphate capsules for 4 weeks, then take a placebo capsule for 4 weeks, while eating a controlled diet. By measuring how well your muscles use energy and how much you can exercise, the researchers hope to learn if cutting back on phosphate could help people stay more active and healthier.
Many people eat too much phosphate without realizing it, and scientists suspect this mineral excess might make muscles less efficient and lead to weight gain in the belly area. This study aims to find out whether lowering phosphate intake could improve fitness and overall health.
You likely qualify if…
You likely don't qualify if…
You will spend about 8 weeks in the study, taking two capsules daily—either the medication or a placebo—for two 4-week periods. You'll be asked to follow a controlled diet during the entire study and have regular check-ins with a research dietitian. You'll complete exercise tests to measure how well your muscles use oxygen and energy, and provide urine samples to make sure you're sticking to the diet plan.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
United States
Sponsor
University of Texas Southwestern Medical Center
Enrollment target
~124 participants
Started
September 2022
Primary completion
March 2027
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
John Giacona, PA-C
Wanpen.Vongpatanasin@UTSouthwestern.edu
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.