Plain-English translation of NCT05152888 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
Researchers want to know whether , a cholesterol-lowering medication, can improve blood flow to your heart muscle in people who have stable coronary artery disease. The study will use special heart imaging scans to measure whether the medication helps your heart get better blood supply. This medication works differently than standard statin drugs and may have additional benefits beyond just lowering cholesterol.
While this medication is known to lower cholesterol and reduce heart attack risk, researchers want to understand exactly how it works and whether it improves the actual blood flow to heart muscle tissue—not just by clearing blockages, but by reducing inflammation and improving how small blood vessels function.
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You would visit the clinic at the start and receive special heart imaging scans (PET and CT scans) to measure your heart's blood flow. Then you would either receive the medication by injection or be observed without it for 12 months. At the end of the year, you would return for repeat imaging scans and blood tests to see if the medication changed how well blood flows to your heart.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States