Plain-English translation of NCT05164328 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The Pro@Heart study is a long-term research project that follows young competitive endurance athletes (and a comparison group of non-athletes) to understand how intense training affects the heart. Researchers will track how your heart's structure, function, and electrical activity change over many years, and connect these changes to your training habits and genes. The goal is to learn whether these heart changes lead to better athletic performance, health benefits, or—in rare cases—heart problems.
Doctors know that intense endurance training causes the heart to enlarge and change shape—a condition called 'athlete's heart.' However, we don't fully understand why these changes happen, how much they vary from person to person, or whether they always stay healthy. This study will help clarify which athletes might be at risk for heart problems and which changes are truly beneficial.
You likely qualify if…
You likely don't qualify if…
You would be part of a long-term study spanning several decades, with regular check-ins at study centers. You would likely undergo heart tests (such as ultrasounds or ECGs), provide blood samples for genetic testing, and answer questions about your training habits and health. The exact schedule and frequency of visits would be explained during enrollment, but the goal is to follow your heart health over a very long time to see how it changes with your athletic activities.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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