Plain-English translation of NCT05170399 on ClinicalTrials.gov ↗ · Source last updated ·
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This research study is testing how well standard vaccines work in people who have been diagnosed with chronic lymphocytic leukemia, lymphoma, or related blood cancers. The study will measure whether vaccines like the flu, pneumonia, shingles, and COVID-19 vaccines create protective immunity in patients with these conditions—and whether the results differ depending on what cancer treatment (if any) a person is receiving.
People with blood cancers often have weakened immune systems, which means vaccines may not work as well for them as they do for healthy people. This study will help doctors understand which patients can safely get vaccinated and when the best time to vaccinate is during their cancer care.
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If you join, you will receive one or more standard vaccines (such as flu, pneumonia, shingles, or COVID-19 vaccines) as part of your regular medical care. After each vaccine series is complete, you will have blood tests to check whether your body created protective antibodies in response to the vaccine. The study will track your immune response over time and compare results across different groups based on your cancer treatment status.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
United States