Plain-English translation of NCT05173714 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing whether a combination of guided strength training and —a medication already approved for weight loss and diabetes—can help people with chronic kidney disease reduce the amount of time they spend sitting and increase physical activity. The study builds on earlier research showing that helping people sit less can improve their kidney health, but the benefits didn't last. The researchers want to see if adding strength training and this medication can make the benefits stick longer.
Sitting for long periods harms kidney function and increases the risk of diabetes, heart disease, and early death. An earlier study showed that a sitting-reduction program worked, but people went back to their old habits. This trial aims to find out whether the medication and structured strength training can help people keep moving more and sitting less over time.
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You would commit to a 12-month study: the first 3 months involve learning the sitting-reduction program, and the next 9 months you would continue that program while also attending guided strength-training sessions. Depending on which group you're randomly assigned to, you would either take or a placebo pill daily. You would wear a small movement tracker and use your smartphone or computer to log your activities. The study includes regular check-ins with the research team at the University of Utah or Stanford University to track your progress and kidney health.
AI-generated summary from trial data · Aug 7, 2026 · Not medical advice
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