Plain-English translation of NCT05174052 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
Phase 3 โ Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether dapagliflozin, a diabetes medication, can help reduce how often your heart experiences atrial fibrillation (an irregular heartbeat). People with both diabetes and atrial fibrillation are at higher risk for heart problems, and researchers believe this medication may have protective effects on the heart beyond helping with blood sugar control. The study will track how much time you spend in irregular rhythms and how the condition affects your quality of life.
While this medication has been shown to protect the heart in many ways, researchers have never specifically studied whether it can prevent or reduce irregular heartbeats in people who have both conditions. This trial will fill that gap and help doctors understand if this treatment could become a new option for patients like you.
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You will be randomly assigned to take either the medication or a placebo (a pill with no active ingredient) once daily for 3 months. You'll wear a small heart rhythm monitoring patch for 2 weeks at the start and end of the study to measure your irregular heartbeats, complete a quality-of-life survey, and have an ultrasound of your heart (echocardiogram) to look at changes in heart structure. The study involves visits at the beginning and end, with researchers tracking how the treatment affects your symptoms and heart health.
AI-generated summary from trial data ยท Jun 5, 2026 ยท Not medical advice
United States