Plain-English translation of NCT05174351 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study investigates what happens when patients with a specific type of heart failure stop taking beta-blockers, a medication commonly prescribed to help the heart. Researchers will compare how you feel and how your heart functions before and after stopping the medication for four weeks. The goal is to understand whether this medication is truly necessary for patients with your type of heart condition.
Some heart medications are prescribed out of habit or because they help other heart problems, but may not be needed for everyone. This trial exists to determine whether this particular medication is actually beneficial for patients with preserved heart function, or whether it could be safely discontinued.
You likely qualify if…
You likely don't qualify if…
You will have two visits spaced four weeks apart. At your first visit (during a regular clinic appointment), the research team will gather baseline information. Four weeks later, you will stop taking your beta-blocker medication and return for a second research visit where you'll complete questionnaires and have a brief heart ultrasound. The study ends after this second visit with no further follow-up required.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States
Sponsor
UConn Health
Enrollment target
~30 participants
Started
December 2021
Primary completion
November 2027
Age range
50 Years – 80 Years
Last updated on clinicaltrials.gov in September 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kai Chen, MD,PhD
UConn Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.