Plain-English translation of NCT05177393 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that gathers real-world information about how esophageal cancer patients are treated at hospitals across Africa. Researchers want to understand what types of treatment patients receive—such as chemotherapy, radiation, surgery, or supportive care—and how well these treatments work for them. By collecting this information from thousands of patients, the study aims to identify which approaches help patients live longer and maintain the best quality of life during and after treatment.
Esophageal cancer is a serious disease, and doctors use many different treatment approaches depending on each patient's situation. However, there is limited information about how these different treatments actually perform in real-world settings, especially in African countries. This study aims to fill that gap by documenting what treatments are used and measuring their real-world impact on patient survival and well-being.
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If you join this study, researchers will access your medical records to learn about your diagnosis, the treatments you received, and how you responded to them. You will also be asked to complete questionnaires about how you felt during and after treatment—such as your ability to eat, any side effects, and your overall quality of life. The study does not involve taking a new medication; instead, it follows your existing care and collects information about the treatments your doctor has already recommended.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Kenya
Malawi
Tanzania
Sponsor
University of California, San Francisco
Collaborators
Westat, African Esophageal Cancer Consortium (AfrECC)
Enrollment target
~2,476 participants
Started
February 2019
Primary completion
June 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Geoffrey Buckle, MD, MPH
University of California, San Francisco
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.