Plain-English translation of NCT05177562 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a large research study led by the University of Oxford that aims to understand what causes polycystic ovary syndrome (PCOS) by studying genes, proteins, and tissues from women with and without the condition. Researchers will analyze blood samples, ovarian tissue, and fat tissue to identify the biological differences that lead to PCOS and its related health problems. This knowledge may help doctors develop new treatments for PCOS in the future.
PCOS is a common condition affecting many women of reproductive age, but doctors still don't fully understand what causes it or why some women develop related health problems like gestational diabetes during pregnancy. By studying the genetics and biology of women with PCOS compared to healthy women, researchers hope to find new drug targets and develop better treatments.
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Participation involves donating blood samples and possibly tissue samples (such as ovarian or fat tissue) that researchers will analyze for genetic and protein information. Depending on which group you join, you may be asked to provide samples once or at multiple visits, and to share information about your medical history and reproductive health. There are no medications to take — the study is purely observational, meaning researchers will study your samples and medical information to look for patterns and biological differences related to PCOS.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
United Kingdom
Sponsor
University of Oxford
Collaborators
Bayer, Li Ka Shing Foundation
Enrollment target
~1,175 participants
Started
October 2021
Primary completion
September 2028
Age range
16 Years – 45 Years
Sex
Female only
Last updated on clinicaltrials.gov in January 2022.
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Central contact
RepOx Research Midwife
University of Oxford
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