Plain-English translation of NCT05182892 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether advanced computer analysis of speech can help doctors adjust deep brain stimulation (a device implanted in your brain to treat Parkinson's motor symptoms) to reduce speech-related side effects. Researchers want to identify which aspects of your speech improve or worsen with stimulation, and use that information to help doctors program your device better in the future.
Deep brain stimulation is very effective at reducing the movement problems of Parkinson's disease, but it often causes speech difficulties as a side effect—affecting up to 90% of patients. Doctors currently rely on listening to patients, which misses subtle changes in speech quality. This trial aims to use precise computer measurement of speech to understand these problems better and find ways to prevent or reduce them.
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You would come to the hospital for testing sessions where researchers record your speech while your brain stimulation is turned off and on at different levels, both with and without your Parkinson's medication (if possible). Computers then analyze your speech in detail to measure exactly how it changes with stimulation. The study has multiple parts: the first identifies which speech measurements are most useful, the second creates brain maps showing which stimulation areas affect speech, and researchers may study additional treatment strategies in a third part.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
Czechia
Switzerland