Plain-English translation of NCT05186623 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Researchers want to understand why some people respond well to medications like for ulcerative colitis, while others don't. This study will collect blood, tissue, and stool samples from 300 patients starting one of these treatments, then use genetic and laboratory data to build a tool that predicts whether the medication will work for you — both in the short term (after a few months) and long term (after a year).
Right now, doctors can't predict in advance who will benefit from these newer medications for ulcerative colitis. This study aims to create a personalized prediction tool so that in the future, doctors can choose the best treatment for each patient from the start, rather than through trial and error.
You likely qualify if…
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You'll visit the clinic before starting your medication for a colonoscopy (camera exam of your colon), blood draw, and stool sample collection. Researchers will follow you at 14–16 weeks and again at 52 weeks to see how well the medication is working through blood tests and another colonoscopy. The study lasts about one year, and your samples and medical information will be used to develop the prediction model.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
South Korea
Enrollment target
~300 participants
Started
February 2022
Primary completion
December 2026
Age range
18 Years – 79 Years
Last updated on clinicaltrials.gov in February 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Byong Duk Ye, MD, PhD
Asan Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.