Plain-English translation of NCT05189496 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether hyperbaric oxygen therapy — treatment in a pressurized chamber with high-concentration oxygen — can prevent a serious lung complication called radiation pneumonitis that sometimes develops after radiation therapy for breast cancer. Radiation therapy is effective at treating breast cancer, but it can damage healthy lung tissue over time. This study will test whether giving patients 30–40 sessions of this oxygen therapy right after their radiation treatment can help prevent or reduce that lung damage and improve their quality of life.
Radiation therapy for breast cancer can cause lasting damage to the lungs, including a condition called pulmonary fibrosis that seriously affects breathing and quality of life. This treatment seeks to determine whether the oxygen therapy can help repair radiation damage and prevent these serious complications from developing.
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If you are assigned to receive the oxygen therapy, you will attend 30 to 40 sessions in a pressurized oxygen chamber, usually starting right after your radiation treatment ends. Each session involves breathing pure oxygen in a special chamber while pressure is gradually increased and then decreased. The control group will not receive this therapy, but both groups will be followed to compare how well the oxygen therapy works at preventing lung complications and to measure its effects on quality of life and survival.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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