Plain-English translation of NCT05193968 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers at Mayo Clinic are studying the connection between hot flashes during menopause and problems with how blood vessels and nerves work in the body. Women who have hot flashes are more likely to develop high blood pressure and heart disease, but scientists don't fully understand why. This study will help fill that gap by looking at how blood vessel and nerve function differ in women who experience hot flashes.
Hot flashes are common during menopause, but doctors have noticed that women with frequent hot flashes face higher risks of cardiovascular problems. Understanding the link between hot flashes and how blood vessels function could lead to better ways to protect women's heart health.
You likely qualify if…
You likely don't qualify if…
You would start with a screening visit to assess how often you experience hot flashes. Then you can choose to participate in one or two optional study visits focused on either blood vessel function or nerve system function. The visits involve non-invasive tests that measure how your blood vessels and nerves respond—no medications are being given in this study.
AI-generated summary from trial data · Oct 12, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Collaborators
National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Enrollment target
~120 participants
Started
February 2022
Primary completion
December 2026
Age range
40 Years – 60 Years
Sex
Female only
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Pamela A Engrav
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.