Plain-English translation of NCT05194111 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
Some cancer treatments, especially certain chemotherapy drugs, can damage the heart over time—even if you feel fine right now. This trial tests whether sacubitril/, a medication that helps the heart pump better, can prevent or slow this damage in young adults who had cancer before age 39. Researchers want to learn if this medication is safe and effective for people in your situation.
Cancer survivors are at risk for heart problems years after treatment ends, but doctors don't yet have proven ways to prevent this damage in younger patients. This study aims to fill that gap by testing whether this medication can protect hearts that show early warning signs of chemotherapy-related damage.
You likely qualify if…
You likely don't qualify if…
If you join, you'll be randomly assigned to take one of three heart medications by mouth twice daily. You'll have regular clinic visits for heart imaging (ultrasounds and possibly MRI scans), blood tests, and a simple six-minute walking test to check your heart function. The study will track how well the medication works and whether it's safe for you over several months.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
United States