Plain-English translation of NCT05196035 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a new medication called finerenone in children ages 6 months to 18 years who have chronic kidney disease and are losing protein in their urine. The medication is designed to work together with medicines your child may already be taking (called ACE inhibitors or ARBs) to better protect the kidneys and reduce protein loss. Researchers want to see if this medication works better than a placebo (a pill with no medicine) when added to your child's current treatment.
Children with chronic kidney disease often lose too much protein in their urine, which can damage their kidneys further. While current standard treatments help, they don't work well enough for all children. This trial exists to see if the new treatment can offer better protection for growing kidneys by working in a different way than medicines already available.
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Your child will visit the study clinic multiple times over 6 months for blood tests, urine tests, and blood pressure checks to monitor kidney health and protein levels. Your child will be randomly assigned to receive either the new medication or a placebo pill (neither you nor the study team will know which one initially), both taken by mouth and adjusted based on your child's age and weight. Throughout the study, researchers will carefully track how well the medication works and watch for any side effects.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States
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