Plain-English translation of NCT05202678 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a procedure called AGN1 LOEP (Local Osteo-Enhancement Procedure) designed to strengthen bone in the hip of women with osteoporosis. The procedure targets the upper thighbone, where bone loss is most common in this condition. Researchers want to see if this treatment is safe and whether it helps reduce pain and improve how well women can move and function in their daily lives.
Osteoporosis causes bones to become weak and brittle, especially in the hip, which puts women at high risk for fractures. This trial exists because current treatments don't work well enough for all patients, and doctors need a new option that can directly strengthen the bone where it's needed most.
You likely qualify if…
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You would receive the AGN1 LOEP procedure on your hip. After that, you would return for follow-up visits at 10 days, 6 weeks, 12 months, and 24 months. At each visit, doctors will check your overall health, assess your pain and mobility with simple physical tests, ask you to walk and stand, and at certain visits take bone density scans and X-rays to see how your bone is healing. The entire study lasts 2 years.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Belgium
Sponsor
AgNovos Healthcare, LLC
Enrollment target
~150 participants
Started
July 2021
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Sex
Female only
Last updated on clinicaltrials.gov in January 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Adam Lowe
AZ Nikolaas
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.