Plain-English translation of NCT05204693 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new approach to exercise for people with left heart failure. Instead of traditional cycling where you push the pedals hard, researchers want to see if 'eccentric exercise'—where you focus on slowly controlling the pedals as they move—might be easier and more effective for your heart. The idea is that this gentler approach might let you exercise at helpful levels without overworking your weakened heart.
People with advanced heart failure often cannot exercise hard enough to see real benefits, because their hearts cannot handle the strain. This new type of exercise might let people work their muscles effectively without putting as much stress on their heart, opening up training possibilities for patients who are otherwise too limited.
You likely qualify if…
You likely don't qualify if…
You would come to the University of Zurich for cycling sessions using special equipment designed for eccentric exercise. Some participants would start with traditional cycling (pushing the pedals), while others would start with the new eccentric method (controlling the pedals as they move). Over several weeks, researchers would track your fitness, strength, and how the exercise affects your heart function to see which approach works better for people with your condition.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Switzerland