Plain-English translation of NCT05213598 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at a specific type of liver disease that can develop in adults who had Fontan surgery — a procedure performed in childhood to treat severe congenital heart disease. Researchers want to understand how this liver disease develops and find new blood tests and other markers that could help doctors better track the disease and make better decisions about transplants in the future.
After Fontan surgery, some patients develop liver problems because of how the heart surgery changes blood flow to the liver. Right now, doctors don't have good, simple blood tests to detect and measure how severe this liver disease is, so this research aims to develop those new tools.
You likely qualify if…
You likely don't qualify if…
You would be asked to provide blood samples and may need a liver tissue biopsy (a small sample of liver tissue taken with a needle) so researchers can measure various markers of liver disease. The study will involve visits to the NIH clinical center where doctors will evaluate your liver health and collect these samples. There is no medication to take, and the main goal is to help researchers better understand and detect this condition in future patients.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States