Plain-English translation of NCT05218278 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After a person survives cardiac arrest (when the heart suddenly stops beating), doctors want to know how well they will recover — especially whether their brain will fully recover. This study looks at a protein called NFL (neurofilament light chain) in the blood at different times after admission to intensive care. The researchers believe that measuring NFL levels might help doctors predict which patients will have a good recovery and which may have lasting problems.
When someone survives cardiac arrest, it can be hard to predict early on whether they will make a full recovery or have lasting brain injury. If doctors could use a simple blood test to predict outcomes, it might help guide treatment decisions and give families more accurate information about what to expect.
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You would have blood samples taken at six different time points during your ICU stay: at 12, 24, 30, 36, 42, and 48 hours after admission. The researchers will measure the NFL protein level in each sample to track how it changes over time. Your neurological outcome (how well your brain recovers) will be assessed using a standard medical scale, and the researchers will analyze whether the protein levels could have predicted your outcome.
AI-generated summary from trial data · Aug 9, 2026 · Not medical advice
Slovenia
Enrollment target
~60 participants
Started
January 2022
Primary completion
December 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2025.
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Central contact
Matej Strnad, MD, PhD
University medical cenetr Maribor
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.