Plain-English translation of NCT05222594 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study aims to understand how different parts of your brain work together to help you understand language and meaning. Researchers will use brain monitoring equipment that's already being placed in your brain as part of your epilepsy treatment, and ask you to complete language tasks while they record your brain's response. This will help scientists create detailed maps of which brain areas handle different types of language processing.
While we know that certain brain areas are important for language, scientists still don't fully understand the precise brain computations that allow us to extract meaning from words. This study will use advanced brain recording methods to answer that question and improve our understanding of how the human brain works.
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Since you will already have brain monitoring equipment in place as part of your epilepsy treatment, researchers will ask you to complete language-related tasks while they record your brain's electrical activity through that same equipment. The study takes advantage of monitoring you're already undergoing, so there are no additional surgical procedures needed. You'll simply be asked to listen to or read language stimuli and respond to questions while researchers measure your brain's response.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Collaborators
Massachusetts Institute of Technology
Enrollment target
~40 participants
Started
April 2021
Primary completion
March 2027
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Evelina Fedorenko, PhD
Massachusetts General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.