Plain-English translation of NCT05226169 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a medication called ferric carboxymaltose, given as a single intravenous infusion, to treat anemia (low red blood cell counts) in people with advanced stomach cancer who are starting chemotherapy. Stomach cancer often causes anemia because of internal bleeding and poor nutrition, and chemotherapy can make it worse. The study will compare people who receive this iron infusion to those who receive standard care with oral iron pills, to see if the infusion works better and is safe.
Many people with advanced stomach cancer develop anemia, which makes them feel weak and tired and can interfere with their ability to tolerate chemotherapy. Oral iron pills don't work well in stomach cancer patients because of digestive problems and ongoing bleeding, so researchers want to see if giving iron directly into the bloodstream is a better option.
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If you join this trial, you will be randomly assigned to either receive an iron infusion (a single 15-minute injection into your vein) or to receive standard care with oral iron pills. You will continue your chemotherapy as planned. The study team will monitor your blood counts, iron levels, and overall health over time to see how well the treatment works and whether you experience any side effects. The trial involves about 330 patients being studied at Asan Medical Center in South Korea.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
South Korea