Plain-English translation of NCT05227547 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand why people with COPD or a history of smoking lose the ability to repair their lungs. This study collects tiny lung tissue samples from people already having lung surgery for cancer to map and study the different cell types involved. By examining these cells closely, scientists hope to discover why lung repair fails in COPD and smoking-related disease.
COPD affects millions of people worldwide and has a very high death rate in severe cases. A key problem is that special repair cells in the lungs stop working properly in people with COPD, but doctors don't yet understand why this happens or how these cells interact with nearby cells. This research aims to fill that gap so that better treatments can be developed.
You likely qualify if…
You likely don't qualify if…
If you qualify, researchers will collect a small sample of lung tissue during your scheduled surgery — no extra surgery is needed. The tissue sample is studied under a microscope to examine the different cell types and how they interact. You will not need to attend extra visits; this is done during your cancer surgery, and the research team handles everything.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
France