Plain-English translation of NCT05228340 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a procedure called flexor tenotomy—a small surgery that adjusts the tendons in your toes—can help prevent diabetic foot ulcers from coming back. People with diabetes often develop curved or claw-like toes, which can put dangerous pressure on the skin and cause painful ulcers. This study compares the surgery to standard care (special shoes and inserts) to see which approach works better at keeping ulcers from returning.
Foot ulcers are one of the most serious complications of diabetes and can sometimes lead to amputation. While doctors can treat ulcers when they happen, preventing them from coming back is even more important. This trial wants to find out if the new treatment can stop these ulcers before they start.
You likely qualify if…
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If you join this trial, you will be randomly assigned to either receive the flexor tenotomy surgery or to continue with standard care such as special shoes and inserts. Both groups will have imaging scans of their feet, pressure measurements taken while walking barefoot, and will answer questions about their quality of life. The study will track whether ulcers come back and how your feet respond to the treatment over time.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Enrollment target
~66 participants
Started
March 2022
Primary completion
February 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2022.
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