Plain-English translation of NCT05230446 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The PRESENT trial is testing whether a minimally invasive procedure using Resolute Onyx stents can safely and effectively treat patients who have blockages in multiple heart arteries. Stents are tiny metal mesh tubes placed inside arteries to keep them open and restore blood flow to the heart. This study will track how well this approach works over one year and compare the results to outcomes from a different type of heart surgery.
Many patients with blockages in multiple heart arteries currently undergo open-heart bypass surgery, which is more invasive and has a longer recovery time. This trial exists to see whether using stents through a catheter-based procedure—which is less invasive—can achieve equally good results and potentially offer patients a safer alternative.
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If you join this trial, you will undergo a catheter-based procedure to place stents in your blocked arteries—similar to a standard cardiac catheterization but designed to open multiple vessels. You will then be followed closely with clinic visits and assessments at 30 days, one year, two years, and five years after the procedure to monitor your heart health, check for any complications, and compare your outcomes to the expected results. The study uses advanced imaging (optical coherence tomography) to guide the stent placement and ensure the best possible results.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
Netherlands