Plain-English translation of NCT05234788 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Hypertension research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called renal denervation using the Iberis Renal Denervation System to treat high blood pressure that remains uncontrolled despite taking multiple medications. The study compares two different ways to access the blood vessels: through the wrist (radial access) versus through the groin (femoral access). Both approaches aim to reduce nerve activity in the kidneys to help lower blood pressure.
Many people with high blood pressure continue to have dangerously high readings even when taking multiple blood pressure medications. This trial is testing whether this new procedure might help patients whose high blood pressure isn't controlled by drugs alone.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to receive the renal denervation procedure through either the wrist or the groin. The procedure itself is done in a hospital setting. After treatment, you will have follow-up visits at 3 months and 6 months to check your blood pressure and overall health. The entire study is expected to last about 38 months from start to finish.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France
Germany