Plain-English translation of NCT05235685 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial investigates why people who have both chronic obstructive pulmonary disease (COPD) and heart failure experience excessive muscle fatigue during exercise. Researchers believe that both conditions reduce oxygen delivery to muscles and the brain, making exercise harder. The study will test whether giving patients extra oxygen or non-invasive breathing support during exercise can improve oxygen delivery and reduce fatigue.
Many people have both lung disease and heart failure at the same time, and they struggle much more with exercise than people with just one condition. Doctors don't fully understand why, but suspect it's because their muscles aren't getting enough oxygen. This trial aims to confirm that theory and test whether simple interventions like extra oxygen or breathing assistance can help.
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You will be asked to exercise on a stationary bike while researchers measure how your muscles perform and how tired they become. If you have both lung disease and heart failure, you'll do the exercise test twice—once breathing regular air and once breathing air with extra oxygen—so researchers can compare how the extra oxygen affects your muscle fatigue. The study involves about 40 participants total and takes place at a university hospital.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
France