Plain-English translation of NCT05238922 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Solid Tumors research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This research study is testing a new drug called INCB123667 to see if it can help people with advanced cancers. Researchers will first test the medication alone, then test it combined with other cancer treatments. They want to find the right dose and understand how well it works against different types of cancer.
Many people with advanced cancers need new treatment options, especially when standard treatments stop working or aren't suitable for them. This medication targets a specific part of cancer cells, and researchers want to see if it can be a helpful new option.
You will take the medication by mouth once daily in 28-day cycles. The study has two main parts: first, researchers test the medication alone to find the safest dose; then, they test it combined with other cancer drugs. You will have regular clinic visits for blood tests, scans, and health monitoring, and you may need tumor biopsies during the study to see how the medication is affecting your cancer.
AI-generated summary from trial data · Aug 8, 2026 · Not medical advice
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