Plain-English translation of NCT05240950 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Colorectal Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new treatment called for people with colorectal cancer that has spread to the liver. The treatment works by taking your own immune cells, engineering them in a lab to recognize and attack cancer cells, and then giving them back to you. This is a Phase 1 study, which means researchers are still learning about the safety and best dose of this medication.
After surgery to remove colorectal cancer and its spread to the liver, some patients still have tiny amounts of cancer cells remaining that can't be seen on scans—but blood tests can detect them. This study exists to see if the new treatment can find and destroy these hidden cancer cells before they grow back into tumors.
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You will come to the hospital for a procedure to collect some of your immune cells from your blood. These cells will be sent to a lab where they will be engineered to recognize your cancer cells, which takes several weeks. Once ready, you will return to receive an infusion of these modified cells back into your body. You will then be monitored closely with blood tests and imaging to see how well the treatment works and to watch for any side effects.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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