Plain-English translation of NCT05242393 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand whether your body's internal clock — the natural rhythms that control sleep, wakefulness, and other functions — plays a role in how your brain heals after an ischemic stroke (when a blood clot blocks blood flow to the brain). The study will look at genetic markers related to circadian rhythms and examine your sleep patterns to see if they're connected to recovery. This is an observational study, meaning researchers will track what naturally happens to you rather than testing a new medication.
After a stroke, your brain has a chance to rewire itself and heal — a process called neuroplasticity. Researchers don't yet know whether your sleep and body clock rhythms affect how well this healing happens. Understanding this connection could lead to better ways to help stroke patients recover.
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If you join, researchers will collect information from your medical records and take a blood sample within the first 2–3 days after your stroke to look at genetic markers related to your body clock. They will also assess your sleep patterns and stroke severity. Then, about 10–14 days after your stroke (around the time you leave the hospital), they will repeat some of these assessments to see how you're recovering. The study also includes a look back at records from stroke patients treated between 2018 and 2022 to see if patterns emerged in their recovery.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
Russia
Sponsor
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health
Enrollment target
~250 participants
Started
May 2018
Primary completion
January 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in August 2025.
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Central contact
Lyudmila Korostovtseva, MD, PHD
Almazov National Medical Research Centre
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.