Plain-English translation of NCT05246475 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing whether a special type of combined scanner — one that does both PET and MRI imaging at the same time — can accurately find areas within head and neck tumors that don't have enough oxygen. Tumors with low-oxygen areas tend to be more aggressive and harder to treat with radiation therapy. The study will compare a radioactive tracer called [18F]EF5-PET with advanced MRI techniques to see which method works best at finding these oxygen-starved regions.
Low-oxygen areas in tumors are known to make cancers more aggressive and resistant to radiation treatment, but current methods for detecting them aren't always reliable or convenient. This research aims to develop better, simpler imaging methods that could help doctors identify these dangerous areas before treatment and plan more effective therapy.
You likely qualify if…
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You will receive one additional imaging scan beyond your standard cancer care. A radioactive tracer will be injected into your arm, and about three hours later, you'll undergo a simultaneous PET-MRI scan (a combined imaging procedure) that takes pictures of your tumor. This scan is for research only and will not affect your regular diagnosis or treatment plan — you'll continue with all your standard medical care as usual.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
Finland
Sponsor
Turku University Hospital
Enrollment target
~30 participants
Started
February 2022
Primary completion
May 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in February 2022.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jussi Hirvonen, MD, PhD
Radiologist
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.