Plain-English translation of NCT05248581 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is building a detailed registry — a medical database — of patients with advanced colorectal cancer that has spread to the liver who undergo living donor liver transplantation. Researchers want to track how well patients do after this surgery, including how long they survive and whether their cancer comes back. By collecting this information, doctors hope to better understand which patients benefit most from this approach and improve outcomes for future patients.
Colorectal cancer that spreads to the liver is very serious and hard to treat with standard surgery. This registry exists to learn whether transplanting a healthy liver from a living donor can help some patients live longer and stay cancer-free, and to identify which patients are most likely to benefit from this treatment.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would proceed with living donor liver transplantation as your treatment. The study involves collecting and storing your medical records, pathology reports, imaging results, and blood samples in a research database. Researchers will follow your progress over time, tracking your survival, whether cancer returns, and other health outcomes to better understand how well this treatment works.
AI-generated summary from trial data · Aug 14, 2026 · Not medical advice
United States
Sponsor
University of Rochester
Enrollment target
~25 participants
Started
August 2019
Primary completion
August 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Roberto Hernandez-Alejandro, MD
University of Rochester
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.