Plain-English translation of NCT05254197 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The SOLOMON Study is tracking patients with benign (non-cancerous) brain tumors to learn more about how these tumors behave over time. Many people with small, symptom-free brain tumors don't need surgery or radiation right away—instead, doctors watch them carefully with repeated MRI scans. This research aims to identify which factors predict whether a tumor will grow, so doctors can make better decisions about when and if treatment is needed.
Very little is known about the natural history of benign brain tumors because they are often treated immediately after diagnosis. However, many small, asymptomatic tumors are better managed with careful observation rather than immediate intervention. This study exists to understand what causes some of these tumors to grow over time and which patients can safely be monitored without treatment.
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Participants will have their medical records reviewed and will complete periodic MRI scans at least 3 months apart to monitor their tumor. The study includes both people with past scans (looking back at their history since 1998) and newly diagnosed patients enrolling from February 2022 onward. No medication or invasive procedures are involved—you simply come in for scheduled brain imaging and allow researchers to track whether your tumor changes over time.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
South Korea
Sponsor
Seoul National University Hospital
Enrollment target
~3,000 participants
Started
January 2001
Primary completion
December 2035
Age range
18 Years and older
Last updated on clinicaltrials.gov in December 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Chul-Kee Park, MD PhD
Seoul National University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.