Plain-English translation of NCT05257681 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a surgical approach called inter-lobar fissure completion for people whose emphysema or COPD symptoms didn't improve enough after receiving endobronchial valves (a non-surgical breathing treatment). The surgery aims to seal off parts of the overinflated lung and remove scar tissue so the healthy lung tissue can expand and work better, helping you breathe more easily.
Some patients receive endobronchial valves to reduce lung volume and improve breathing, but the procedure doesn't work well for everyone—especially when scar tissue builds up or air leaks around the valve. This trial explores whether surgery can help these patients who didn't get relief from the valve treatment alone.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will undergo a minimally invasive chest surgery (performed by a thoracic surgeon using a camera-guided approach) to complete the lung fissure and remove scar tissue. You will then have follow-up visits at 3 months, during which doctors will perform breathing tests, imaging scans, and ask you to complete questionnaires about your breathing and quality of life to see if the surgery helped.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States