Plain-English translation of NCT05263076 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing uterine transplantation — surgery to place a healthy uterus from a donor into women who were born without one or had theirs removed due to disease. Researchers hope this will allow these women to become pregnant and have biological children. The transplanted uterus would come from either a living donor (like a family member) or a deceased donor.
Some women have a condition called absolute uterine factor infertility, meaning they cannot have children because they don't have a functioning uterus. This treatment offers them a new option to experience pregnancy and childbirth, rather than only adoption or using a surrogate.
You likely qualify if…
You likely don't qualify if…
First, you would complete extensive evaluations with multiple specialists — including fertility doctors, surgeons, and mental health professionals — to make sure you are physically and emotionally ready. You would then undergo IVF to create and freeze embryos. Once you have enough healthy embryos and are cleared by the team, you would have surgery to receive the transplanted uterus. After transplant, you would take anti-rejection medications for life and be monitored closely before and during pregnancy. The study team would follow your health and your child's development for years after birth.
AI-generated summary from trial data · Aug 20, 2026 · Not medical advice
United States