Plain-English translation of NCT05265520 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a newer pacemaker approach called His-bundle pacing compared to the standard pacemaker approach for people with heart failure and a condition called right bundle-branch block. The goal is to see whether the newer pacemaker technique can better improve how well your heart pumps blood and improve your symptoms and quality of life. You would receive one of these two pacemaker types and be followed for up to 2 years.
Some people with heart failure and right bundle-branch block don't improve well enough with standard pacemakers. Doctors believe that pacing a different part of the heart's electrical system might work better, but this newer approach needs to be carefully tested and compared to the standard treatment.
You likely qualify if…
You likely don't qualify if…
You would have a pacemaker device surgically implanted—either the newer His-bundle pacing type or the standard approach—and then be randomly assigned to one group or the other. You would return for follow-up visits at 6 months, 12 months, and 24 months to have heart tests (ultrasounds and heart rhythm tracings), blood work, and assessments of your symptoms and quality of life. The study is being conducted at multiple medical centers across the country.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
United States