Plain-English translation of NCT05269459 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our PTSD research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research trial is testing cannabidiol (CBD)—a non-intoxicating compound derived from cannabis—to see if it can help reduce the symptoms of post-traumatic stress disorder (PTSD) in adults. Researchers want to understand whether this medication is safe and effective at reducing common PTSD symptoms like flashbacks, sleep problems, and feeling on edge. The study will compare the medication to a placebo (a dummy pill) to see which works better.
Many people with PTSD struggle with current treatments, and some don't get enough relief from their symptoms. This trial exists to explore whether this medication could offer a new treatment option for people dealing with the lasting effects of trauma.
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If you join this study, you will either receive the study medication or a placebo pill twice daily for a set period. You will attend study visits where researchers will check on your symptoms, mood, sleep, and overall quality of life using questionnaires and possibly brain imaging scans. Throughout the study, your mental health and any side effects will be monitored carefully to ensure your safety.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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