Plain-English translation of NCT05271669 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study is tracking how COVID-19 immunity works at the household level — meaning how it spreads and protects people within families. Researchers will check your vaccination status, test your blood for antibodies (signs of past infection or vaccination protection), and ask about your COVID-19 history. They want to understand how immunity changes over time and how well people in families are protected against the virus.
As the pandemic continues, scientists need to understand how long COVID-19 protection lasts in real families and how many people stay vaccinated. This information will help public health leaders make better decisions about boosters and protection strategies.
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You and your household members would visit a research center three times over the course of about 12–18 months. At each visit, you'll have a small blood sample taken and complete a simple questionnaire about your vaccination history, any COVID-19 infections, and the precautions you've taken. The whole process is designed to be straightforward and low-burden.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
China
~1,350 participants
Started
June 2022
Primary completion
July 2026
Last updated on clinicaltrials.gov in March 2026.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.