Plain-English translation of NCT05272618 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research is trying to understand a type of heart attack that happens even when the large heart arteries are not blocked. Researchers will use specialized heart imaging tests and blood vessel function assessments to identify which patients have problems in their smallest blood vessels (called microvascular dysfunction). The study will follow 150 patients for 2 years to learn how this condition affects their health and recovery.
About 5–10% of heart attack patients have clear, unblocked arteries, yet they still have serious symptoms. Doctors don't fully understand why this happens or how to treat it best. This study exists to identify the root cause in each patient—especially problems with tiny blood vessels—so doctors can provide the right treatment and predict outcomes more accurately.
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You will undergo specialized heart imaging and blood vessel function tests—some invasive (using catheters placed in heart vessels) and some non-invasive (like PET scans or ultrasound). These tests help doctors determine whether you have microvascular dysfunction. You will be followed for 2 years with clinic visits and health outcome assessments to see how your condition progresses and how well different treatments work. The study aims to enroll 150 patients and is currently recruiting.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
South Korea
Sponsor
Chonnam National University Hospital
Collaborators
Korean Cardiac Research Foundation, Abbott
Enrollment target
~150 participants
Started
February 2022
Primary completion
December 2029
Age range
19 Years and older
Last updated on clinicaltrials.gov in May 2026.
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Central contact
Young Joon Hong, MD, PhD
Chonnam National University Medical School; Chonnam National University Hospital
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