Plain-English translation of NCT05276050 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help people with schizophrenia quit smoking. Researchers believe that schizophrenia and nicotine addiction affect some of the same brain circuits, so targeting those circuits with this magnetic stimulation tool might help reduce smoking and improve overall health. The study will compare two different types of magnetic coils to see which works better for people with schizophrenia who want to stop smoking.
People with schizophrenia smoke at much higher rates than the general population, and standard smoking-cessation treatments often don't work as well for them. This trial exists to develop a more targeted approach using brain stimulation technology that addresses the overlapping brain circuitry involved in both schizophrenia and nicotine addiction.
You likely qualify if…
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If you join this study, you will receive brain stimulation treatment sessions using magnetic coils applied to your scalp—a painless procedure similar to wearing a special cap. You'll be randomly assigned to receive one of two types of magnetic coil treatments designed to help with smoking cessation. Throughout your participation, you'll need to abstain from alcohol, marijuana, and cigarettes for set periods before each session, keep in touch with study staff, and allow researchers to communicate with your healthcare providers.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
The University of Texas Health Science Center, Houston
Collaborators
National Institute on Drug Abuse (NIDA)
Enrollment target
~50 participants
Started
June 2022
Primary completion
July 2026
Age range
22 Years – 65 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Xiaoming Du, PhD
The University of Texas Health Science Center, Houston
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.