Plain-English translation of NCT05276050 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help people with schizophrenia quit smoking. Researchers believe that schizophrenia and nicotine addiction affect some of the same brain circuits, so targeting those circuits with this magnetic stimulation tool might help reduce smoking and improve overall health. The study will compare two different types of magnetic coils to see which works better for people with schizophrenia who want to stop smoking.
People with schizophrenia smoke at much higher rates than the general population, and standard smoking-cessation treatments often don't work as well for them. This trial exists to develop a more targeted approach using brain stimulation technology that addresses the overlapping brain circuitry involved in both schizophrenia and nicotine addiction.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will receive brain stimulation treatment sessions using magnetic coils applied to your scalp—a painless procedure similar to wearing a special cap. You'll be randomly assigned to receive one of two types of magnetic coil treatments designed to help with smoking cessation. Throughout your participation, you'll need to abstain from alcohol, marijuana, and cigarettes for set periods before each session, keep in touch with study staff, and allow researchers to communicate with your healthcare providers.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States