Plain-English translation of NCT05277025 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at how pain works differently in two common chronic pain conditions: fibromyalgia and rheumatoid arthritis. Researchers believe these conditions involve different pain mechanisms in the body, and this study aims to understand those differences by testing and comparing pain processing in people with each condition, as well as in healthy volunteers.
Fibromyalgia and rheumatoid arthritis cause pain through different pathways in the body—one involves how the nervous system processes pain signals, while the other involves inflammation in the joints. By studying these differences, researchers hope to develop better treatments tailored to how each condition actually works.
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As a participant, you would come in for testing sessions where researchers will assess how your body processes pain using specialized tests and measurements. The study compares results between people with fibromyalgia, people with rheumatoid arthritis, and healthy volunteers to identify the differences in pain mechanisms. Your involvement would help scientists understand why these conditions feel different and how to treat them more effectively.
AI-generated summary from trial data · Aug 26, 2026 · Not medical advice
United States
Enrollment target
~150 participants
Started
March 2022
Primary completion
July 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in August 2026.
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Central contact
Roland Staud, M.D.
University of Florida
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.