Plain-English translation of NCT05277025 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how pain works differently in two common conditions: fibromyalgia and rheumatoid arthritis. Fibromyalgia causes widespread pain that comes from how the nervous system processes pain signals, while rheumatoid arthritis causes pain from inflamed joints. This study will help doctors understand whether these conditions involve different pain mechanisms or if they share some similarities.
Fibromyalgia and rheumatoid arthritis are treated very differently because doctors believe they involve different types of pain, but researchers aren't sure if patients might experience both types at the same time. This study aims to clarify how pain actually develops in each condition so doctors can create better treatments.
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You will be divided into one of three groups: fibromyalgia patients, rheumatoid arthritis patients, or healthy volunteers. Researchers will use tests and measurements to study how your body processes pain signals. The study will help them compare pain mechanisms across these groups, though the specific visit schedule and duration are not detailed in the current trial information.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Enrollment target
~150 participants
Started
March 2022
Primary completion
February 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in April 2026.
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Central contact
Roland Staud, M.D.
University of Florida
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