Plain-English translation of NCT05277519 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Stroke research guide →This research study is testing a treatment called functional muscle tendon vibrations — gentle, targeted vibrations applied to muscles — to see if it can help your brain rewire and recover movement after a stroke or traumatic brain injury. About half of participants will receive active vibrations, and half will receive sham (fake) vibrations. Researchers will measure changes in your brain activity, muscle function, and movement ability throughout the study.
After a stroke or traumatic brain injury, the brain sometimes struggles to regain control of movement on one side of the body. This treatment explores whether the vibrations can stimulate the brain's natural ability to rewire itself and restore movement and function in affected limbs.
You likely qualify if…
You likely don't qualify if…
You'll visit the rehabilitation center three times per week for 5 weeks. At the start, midway through, and at the end of the study, you'll have brain scans (MRI), electrical tests of your muscle and brain activity (EMG and EEG), and physical assessments of your movement and walking ability. During each weekly session, you'll receive either real vibration therapy or sham (fake) vibrations applied to your leg muscles — you won't know which group you're in. The entire study lasts about 6 months from your injury.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
France
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Enrollment target
~56 participants
Started
June 2022
Primary completion
June 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Veronique Marchand-Pauvert, PhD
Sorbonne University - AP-HP (Pitié-Salpêtrière Hospital)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.