Plain-English translation of NCT05284643 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a special kind of MRI scan—called spectroscopic MRI—can help doctors find and target hidden cancer cells in the brain more accurately. You would receive proton radiation therapy (a precise form of radiation treatment), guided by these detailed MRI images, along with a medication called . The goal is to kill more cancer cells while minimizing damage to healthy brain tissue.
Glioblastoma that comes back after initial treatment is very challenging to treat. This trial is exploring whether using advanced imaging to better see where the cancer is hiding can help doctors deliver stronger, more targeted radiation therapy to kill remaining cancer cells more effectively.
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You would receive a specialized MRI scan to map out your tumor in detail. Then you would undergo proton radiation therapy delivered in 10 treatment sessions over a few weeks, with the radiation dose carefully guided by your MRI images. You would also receive , a medication given by injection, with your doctor deciding the exact timing and number of doses. The study will monitor your health and the tumor's response through follow-up visits and imaging over time.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States