Plain-English translation of NCT05287126 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ulcerative Colitis research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called to see if it can safely and effectively treat moderate to severe ulcerative colitis in teenagers between ages 12 and 18. Researchers want to understand how well the medication works, how the body processes it, and what side effects might occur. Participants who complete the initial 52-week study period can continue taking the medication for up to an additional 4 years if they choose.
Ulcerative colitis is a serious condition that causes inflammation in the colon and can severely affect young people's quality of life. This trial exists to see whether this new treatment option can help teenagers with moderate to severe disease who may not have responded well to other available treatments.
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You would take the medication as directed for 52 weeks while researchers monitor your progress through regular clinic visits, blood tests, and assessments of your symptoms. During this time, doctors will check how well the medication is working and watch for any side effects. If you and your doctor decide to continue, you have the option to keep taking the medication in an extended phase that can last up to 4 additional years.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
United States