Plain-English translation of NCT05296941 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a brush biopsy — a gentle, non-invasive procedure using a small brush to collect cells from the inside of your mouth — can reliably detect early warning signs of oral cancer. The study compares this brush biopsy method to standard care to see if it's an effective way to catch potentially dangerous mouth lesions before they become cancer.
Oral cancer in Sweden is diagnosed much later than it should be, when survival rates are much lower. Many cases start as visible warning signs in the mouth (like white or red patches) that could be caught early with better screening. This study aims to create an organized screening program so high-risk patients don't miss the chance to catch these changes when treatment is most successful.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will receive either a brush biopsy at the start and again at 3 or 6 months, or standard care with a surgical biopsy only if needed. The brush biopsy is quick and painless — the doctor gently brushes the inside of your mouth to collect a small tissue sample. You'll have follow-up visits to monitor your mouth lesion and catch any changes early.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
Sweden
Collaborators
Uppsala University
Enrollment target
~200 participants
Started
August 2023
Primary completion
December 2029
Age range
18 Years and older
Last updated on clinicaltrials.gov in September 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Kristina Edman, PhD
Uppsala University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.