Plain-English translation of NCT05299710 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study offers girls facing cancer treatment—chemotherapy, radiation, or surgery—a way to preserve their ability to have children in the future. Doctors will surgically remove a small piece of ovarian tissue and freeze it using a special process called cryopreservation. The frozen tissue may be used later in life if experimental fertility restoration techniques become available.
Many cancer treatments can damage or destroy a girl's eggs, making it impossible to become pregnant naturally later in life. This trial is testing whether freezing ovarian tissue before cancer treatment begins offers a safe way to preserve fertility options for young patients who might otherwise lose this ability.
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Before your cancer treatment starts, you will have a brief surgical procedure called laparoscopy, performed under general anesthesia, to remove a small piece of tissue from one ovary. This tissue will be frozen and stored for your future use. You may also be asked to donate a tiny sample of ovarian tissue for research to help improve freezing methods. After surgery, you will be enrolled in a long-term registry where you'll answer yearly surveys about your health and fertility outcomes.
AI-generated summary from trial data · Sep 5, 2026 · Not medical advice
United States
Sponsor
Erin Rowell
Collaborators
Ann & Robert H Lurie Children's Hospital of Chicago
Enrollment target
~250 participants
Started
May 2018
Primary completion
December 2030
Sex
Female only
Last updated on clinicaltrials.gov in September 2026.
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Central contact
Sara Reyes
Lurie Childrens Hospital
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