Plain-English translation of NCT05303896 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →The RELAX study is looking at heart tissue from people with severe heart failure to understand what happens inside the heart as the disease progresses. Researchers will examine the structure and function of failing hearts to identify the cellular changes that occur. This knowledge could help doctors develop better treatments and improve care for future patients with heart failure.
Heart failure remains a serious disease with high death rates, even with current treatments. By studying actual heart tissue from patients, researchers hope to unlock the hidden mechanisms of how hearts fail and what changes occur at the cellular level—information that could lead to better therapies.
You likely qualify if…
You likely don't qualify if…
As a participant, you would be enrolled at Oslo University Hospital. Because this study involves examining heart tissue, participation would occur as part of your heart transplant procedure if you receive one. The research team will collect and analyze samples from your failing heart to study the cellular and structural changes that have occurred, helping them understand heart failure better.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Norway
Enrollment target
~200 participants
Started
May 2022
Primary completion
July 2030
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Henrik Dukefoss, MD
University of Oslo, Oslo University Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.