Plain-English translation of NCT05304962 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Breast Cancer research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is one of the first times this treatment has been tested in people.
This is an early-stage trial testing a new drug called for people with a specific type of advanced breast cancer (hormone-receptor positive, HER2-negative) that has stopped responding to standard treatments. You would take the medication by mouth, either alone or combined with hormone therapy you may already be using. Researchers want to understand how safe the medication is, how your body processes it, and whether it can help slow or stop your cancer.
People with this type of breast cancer often stop responding to current standard treatments over time, leaving few good options. This trial is exploring whether this medication could help patients whose cancer has become resistant to the drugs typically used first.
You likely qualify if…
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You would visit the clinic regularly for check-ups, blood work, and imaging scans to monitor your cancer and how well you tolerate the medication. You would take the oral medication (a pill) at home on a daily schedule determined by the research team. The trial involves an initial dose-escalation phase where researchers slowly increase the dose to find the right level, followed by treatment at the dose determined to be safe and effective.
AI-generated summary from trial data · Aug 19, 2026 · Not medical advice
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