Improving care for high-risk chronic lung disease patients in primary care

Plain-English translation of NCT05306743 on ClinicalTrials.gov ↗ · Source last updated October 2023 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

PREVAIL is a study testing whether a quality improvement program called CONQUEST can help primary care teams better care for people with high-risk chronic obstructive pulmonary disease (COPD). The program uses electronic medical records to identify patients who need better treatment and monitoring. Researchers want to see if this targeted approach reduces health problems and improves outcomes for people living with COPD.

Many people with COPD don't get diagnosed early enough, and even after diagnosis, some patients with frequent flare-ups or severe symptoms aren't getting the care they need. This trial exists to test whether a focused quality improvement program can help catch and better manage these high-risk patients before serious complications happen.

Do you qualify?

You likely qualify if…

you are part of a primary care practice team that can participate as a unified group
your practice has enough patients with high-risk COPD to make the program meaningful
you are willing to be randomly assigned to either receive the new program right away or usual care initially

You likely don't qualify if…

your practice is planning to switch electronic health record systems during the study
your practice is changing ownership during the study period
your practice is already involved in other COPD research studies or quality improvement programs that might interfere

What participation looks like

Your primary care practice team would be randomly assigned to either receive the CONQUEST quality improvement program immediately or to continue with usual care until later. If your practice is in the immediate group, your team would use the program to review electronic medical records and identify high-risk COPD patients, then provide them with targeted, individualized care according to treatment guidelines. The delayed group would receive the same program after the initial evaluation period ends.

AI-generated summary from trial data · Jun 5, 2026 · Not medical advice

Trial locations(3 sites)

United States

University of Colorado, Denver, Colorado

Mount Sinai, New York, New York

MetroHealth, Cleveland, Ohio