Plain-English translation of NCT05307055 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Parkinson Disease research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to program deep brain stimulation devices in people who already have them implanted for Parkinson's disease. Researchers want to see if switching to a different stimulation pattern — called theta burst stimulation — can help improve both thinking abilities and movement better than the current standard approach. The study will compare how you feel and perform with both the new pattern and your current settings over a full year.
People with Parkinson's disease often struggle with both movement problems and thinking difficulties, and current brain stimulation settings don't always address both of these challenges equally well. This trial is exploring whether this new stimulation pattern might offer better improvements in both areas.
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You would visit the clinic multiple times over one year to have your brain stimulation settings adjusted and to complete thinking and movement tests. For the first three weeks, you'll try both the new theta burst pattern and your current settings for one week each, with tests in between. Then for six months, you'll alternate between the two settings every three months with testing each time. Finally, you'll spend six months on the new theta burst pattern. Some visits may also include brain imaging scans if your implant allows it.
AI-generated summary from trial data · Jun 10, 2026 · Not medical advice
United States